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Barbara Alexander, PhD
Billy S. Guyton Distinguished Professor |
Areas of expertise
- General: Cardiovascular/renal physiology, biochemistry
- Specific: Developmental programming of adult health and disease, low birth weight, intrauterine growth restriction, sex differences, hypertension
Research methods
Our laboratory utilizes whole animal and molecular approaches including acute and chronic measurements of arterial pressure and renal hemodynamics (telemetry, GFR, ERPF, RVR), molecular, and biochemical assays (PCR, Western Blot, ELISA, etc).
Current projects
- Renal mechanisms of fetal programming of hypertension
- Mechanisms by which sex hormones contribute to sex differences in hypertension programmed by developmental insult
- Mismatch of prenatal and postnatal nutrition on later cardiovascular risk
- Mechanisms responsible for increased sensitivity to renal injury in low birth weight